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Tuesday, June 5, 2012

Atrial Fibrillation

  1. Risk factors (1/10/12)
    1. " In multivariable-adjusted models, individuals in the lowest quartile of serum magnesium were ~50% more likely to develop AF (adjusted hazard ratio, 1.52; 95% confidence interval, 1.00–2.31; P=0.05) compared with those in the upper quartiles. " (Circulation.2013; 127: 33-38, 1/10/12)
  2. Treatment (1/10/12)
    1. After adjusting for covariates, we found that the effect of rhythm vs rate control drugs changed over time: after a small increase in mortality for patients treated with rhythm control in the 6 months following treatment initiation (hazard ratio [HR], 1.07; 95% CI, 1.01-1.14), the mortality was similar between the 2 groups until year 4 but decreased steadily in the rhythm control group after year 5 (HR, 0.89; 95% CI, 0.81-0.96; and HR, 0.77; 95% CI, 0.62-0.95, after 5 and 8 years, respectively). ( Arch Intern Med. 2012;():1-8. doi:10.1001/archinternmed.2012.2266, 6/5/12)

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